Septin-7 (SEPTIN7)

About Septin-7

Septin-7 (SEPTIN7) is a protein from Homo sapiens identified by UniProt accession Q16181, 437 residues long. MolForge cross-references it against 0 known binders and 85 disease associations.

Target properties

Protein name	Septin-7
UniProt accession	Q16181
Gene	SEPTIN7
Organism	Homo sapiens
Length	437 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (85)

Diseases linked to this target (Open Targets).

platelet count · score 0.36
platelet crit · score 0.32
non-small cell lung carcinoma · score 0.30
disease prognosis measurement · score 0.30
electrocardiography · score 0.06
breast cancer · score 0.06
leukocyte count · score 0.06
lymphocyte count · score 0.06
neutrophil count · score 0.06
C-reactive protein measurement · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q16181-F1	alphafold	PREDICTED	80.19	—

Amino-acid sequence (437 residues)

MSVSARSAAA EERSVNSSTM VAQQKNLEGY VGFANLPNQV YRKSVKRGFE FTLMVVGESG LGKSTLINSL FLTDLYSPEY PGPSHRIKKT VQVEQSKVLI KEGGVQLLLT IVDTPGFGDA VDNSNCWQPV IDYIDSKFED YLNAESRVNR RQMPDNRVQC CLYFIAPSGH GLKPLDIEFM KRLHEKVNII PLIAKADTLT PEECQQFKKQ IMKEIQEHKI KIYEFPETDD EEENKLVKKI KDRLPLAVVG SNTIIEVNGK RVRGRQYPWG VAEVENGEHC DFTILRNMLI RTHMQDLKDV TNNVHYENYR SRKLAAVTYN GVDNNKNKGQ LTKSPLAQME EERREHVAKM KKMEMEMEQV FEMKVKEKVQ KLKDSEAELQ RRHEQMKKNL EAQHKELEEK RRQFEDEKAN WEAQQRILEQ QNSSRTLEKN KKKGKIF

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards