Proline-rich protein 4 (PRR4)

About Proline-rich protein 4

Proline-rich protein 4 (PRR4) is a protein from Homo sapiens identified by UniProt accession Q16378, 134 residues long. MolForge cross-references it against 0 known binders and 17 disease associations.

Target properties

Protein name	Proline-rich protein 4
UniProt accession	Q16378
Gene	PRR4
Organism	Homo sapiens
Length	134 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (17)

Diseases linked to this target (Open Targets).

blood protein measurement · score 0.07
sensory perception of bitter taste · score 0.04
coffee consumption measurement · score 0.02
coffee consumption · score 0.02
COVID-19 · score 0.02
bronchiectasis · score 0.01
Bronchiectasis · score 0.01
dry eye syndrome · score 0.01
infect · score 0.01
infection · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q16378-F1	alphafold	PREDICTED	64.03	—

Amino-acid sequence (134 residues)

MLLVLLSVVL LALSSAQSTD NDVNYEDFTF TIPDVEDSSQ RPDQGPQRPP PEGLLPRPPG DSGNQDDGPQ QRPPKPGGHH RHPPPPPFQN QQRPPRRGHR QLSLPRFPSV SLQEASSFFQ RDRPARHPQE QPLW

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards