Neuronatin (NNAT)

About Neuronatin

Neuronatin (NNAT) is a protein from Homo sapiens identified by UniProt accession Q16517, 81 residues long. MolForge cross-references it against 0 known binders and 98 disease associations.

Target properties

Protein name	Neuronatin
UniProt accession	Q16517
Gene	NNAT
Organism	Homo sapiens
Length	81 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (98)

Diseases linked to this target (Open Targets).

rheumatoid arthritis · score 0.05
exercise-induced hyperinsulinism · score 0.05
hyperinsulinemic hypoglycemia, familial, 2 · score 0.05
vital capacity · score 0.05
chronic pancreatitis · score 0.05
hyperinsulinemic hypoglycemia, familial, 1 · score 0.04
hyperinsulinism due to INSR deficiency · score 0.04
hyperinsulinism-hyperammonemia syndrome · score 0.04
Down syndrome · score 0.04
Ataxia-telangiectasia · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q16517-F1	alphafold	PREDICTED	67.59	—

Amino-acid sequence (81 residues)

MAAVAAASAE LLIIGWYIFR VLLQVFLECC IYWVGFAFRN PPGTQPIARS EVFRYSLQKL AYTVSRTGRQ VLGERRQRAP N

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards