About Cysteine and glycine-rich protein 2
Cysteine and glycine-rich protein 2 (CSRP2) is a protein
from Homo sapiens identified by UniProt accession
Q16527, 193 residues long.
MolForge cross-references it against 0 known binders and
70 disease associations.
Target properties
| Protein name | Cysteine and glycine-rich protein 2 |
|---|
| UniProt accession | Q16527 |
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| Gene | CSRP2 |
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| Organism | Homo sapiens |
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| Length | 193 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (70)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.42
- metabolite measurement · score 0.15
- acute myeloid leukemia · score 0.08
- achalasia-alacrima syndrome · score 0.07
- neoplasm · score 0.07
- appendicular lean mass · score 0.06
- left ventricular noncompaction · score 0.06
- familial cylindromatosis · score 0.04
- Moyamoya disease · score 0.04
- head and neck squamous cell carcinoma · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q16527-F1 | alphafold | PREDICTED | 70.56 | — |
Amino-acid sequence (193 residues)
MPVWGGGNKC GACGRTVYHA EEVQCDGRSF HRCCFLCMVC RKNLDSTTVA IHDEEIYCKS CYGKKYGPKG YGYGQGAGTL NMDRGERLGI KPESVQPHRP TTNPNTSKFA QKYGGAEKCS RCGDSVYAAE KIIGAGKPWH KNCFRCAKCG KSLESTTLTE KEGEIYCKGC YAKNFGPKGF GYGQGAGALV HAQ
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