Large ribosomal subunit protein uL23m (MRPL23)

About Large ribosomal subunit protein uL23m

Large ribosomal subunit protein uL23m (MRPL23) is a protein from Homo sapiens identified by UniProt accession Q16540, 153 residues long. MolForge cross-references it against 0 known binders and 44 disease associations.

Target properties

Protein name	Large ribosomal subunit protein uL23m
UniProt accession	Q16540
Gene	MRPL23
Organism	Homo sapiens
Length	153 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (44)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.44
body height · score 0.32
alcohol drinking · score 0.27
systolic blood pressure · score 0.24
appendicular lean mass · score 0.22
smoking status measurement · score 0.19
mean arterial pressure · score 0.17
DNA methylation · score 0.16
memory impairment · score 0.13
diastolic blood pressure · score 0.13

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q16540-F1	alphafold	PREDICTED	92.33	—

Amino-acid sequence (153 residues)

MARNVVYPLY RLGGPQLRVF RTNFFIQLVR PGVAQPEDTV QFRIPMEMTR VDLRNYLEGI YNVPVAAVRT RVQHGSNKRR DHRNVRIKKP DYKVAYVQLA HGQTFTFPDL FPEKDESPEG SAADDLYSML EEERQQRQSS DPRRGGVPSW FGL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards