Interleukin-17A (IL17A)

About Interleukin-17A

Interleukin-17A (IL17A) is a protein from Homo sapiens identified by UniProt accession Q16552, 155 residues long. MolForge cross-references it against 0 known binders and 1,747 disease associations.

Target properties

Protein name	Interleukin-17A
UniProt accession	Q16552
Gene	IL17A
Organism	Homo sapiens
Length	155 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Approved drugs hitting this target (3)

DrugCentral-linked approved drugs that act on this protein.

Disease associations (1747)

Diseases linked to this target (Open Targets).

psoriasis · score 0.64
psoriatic arthritis · score 0.61
ankylosing spondylitis · score 0.60
psoriasis vulgaris · score 0.56
immune system disease · score 0.51
spondyloarthropathy · score 0.50
hidradenitis suppurativa · score 0.42
rheumatoid arthritis · score 0.41
Vitiligo · score 0.39
Arthritis · score 0.39

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q16552-F1	alphafold	PREDICTED	84.34	—

Amino-acid sequence (155 residues)

MTPGKTSLVS LLLLLSLEAI VKAGITIPRN PGCPNSEDKN FPRTVMVNLN IHNRNTNTNP KRSSDYYNRS TSPWNLHRNE DPERYPSVIW EAKCRHLGCI NADGNVDYHM NSVPIQQEIL VLRREPPHCP NSFRLEKILV SVGCTCVTPI VHHVA

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards