Histone-binding protein RBBP7 (RBBP7)

About Histone-binding protein RBBP7

Histone-binding protein RBBP7 (RBBP7) is a protein from Homo sapiens identified by UniProt accession Q16576, 425 residues long. MolForge cross-references it against 0 known binders and 71 disease associations.

Target properties

Protein name	Histone-binding protein RBBP7
UniProt accession	Q16576
Gene	RBBP7
Organism	Homo sapiens
Length	425 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (71)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.50
viral disease · score 0.46
melanoma · score 0.41
cancer · score 0.38
breast carcinoma · score 0.37
endometrial cancer · score 0.29
breast adenocarcinoma · score 0.28
ovarian cancer · score 0.26
head and neck squamous cell carcinoma · score 0.25
pancreatic adenocarcinoma · score 0.25

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q16576-F1	alphafold	PREDICTED	90.74	—

Amino-acid sequence (425 residues)

MASKEMFEDT VEERVINEEY KIWKKNTPFL YDLVMTHALQ WPSLTVQWLP EVTKPEGKDY ALHWLVLGTH TSDEQNHLVV ARVHIPNDDA QFDASHCDSD KGEFGGFGSV TGKIECEIKI NHEGEVNRAR YMPQNPHIIA TKTPSSDVLV FDYTKHPAKP DPSGECNPDL RLRGHQKEGY GLSWNSNLSG HLLSASDDHT VCLWDINAGP KEGKIVDAKA IFTGHSAVVE DVAWHLLHES LFGSVADDQK LMIWDTRSNT TSKPSHLVDA HTAEVNCLSF NPYSEFILAT GSADKTVALW DLRNLKLKLH TFESHKDEIF QVHWSPHNET ILASSGTDRR LNVWDLSKIG EEQSAEDAED GPPELLFIHG GHTAKISDFS WNPNEPWVIC SVSEDNIMQI WQMAENIYND EESDVTTSEL EGQGS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards