Zinc finger protein 239 (ZNF239)

About Zinc finger protein 239

Zinc finger protein 239 (ZNF239) is a protein from Homo sapiens identified by UniProt accession Q16600, 458 residues long. MolForge cross-references it against 0 known binders and 25 disease associations.

Target properties

Protein name	Zinc finger protein 239
UniProt accession	Q16600
Gene	ZNF239
Organism	Homo sapiens
Length	458 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (25)

Diseases linked to this target (Open Targets).

type 2 diabetes mellitus · score 0.27
coronary artery disease · score 0.12
myocardial infarction · score 0.12
cortical surface area measurement · score 0.10
brain measurement · score 0.10
angina pectoris · score 0.10
heel bone mineral density · score 0.09
coronary artery bypass · score 0.08
vertebral disorder · score 0.07
cystatin C measurement · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q16600-F1	alphafold	PREDICTED	62.58	—

Amino-acid sequence (458 residues)

MASTITGSQD CIVNHRGEVD GEPELDISPC QQWGEASSPI SRNRDSVMTL QSGCFENIES ETYLPLKVSS QIDTQDSSVK FCKNEPQDHQ ESRRLFVMEE STERKVIKGE SCSENLQVKL VSDGQELASP LLNGEATCQN GQLKESLDPI DCNCKDIHGW KSQVVSCSQQ RAHTEEKPCD HNNCGKILNT SPDGHPYEKI HTAEKQYECS QCGKNFSQSS ELLLHQRDHT EEKPYKCEQC GKGFTRSSSL LIHQAVHTDE KPYKCDKCGK GFTRSSSLLI HHAVHTGEKP YKCDKCGKGF SQSSKLHIHQ RVHTGEKPYE CEECGMSFSQ RSNLHIHQRV HTGERPYKCG ECGKGFSQSS NLHIHRCIHT GEKPYQCYEC GKGFSQSSDL RIHLRVHTGE KPYHCGKCGK GFSQSSKLLI HQRVHTGEKP YECSKCGKGF SQSSNLHIHQ RVHKKDPR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards