About Extracellular matrix protein 1
Extracellular matrix protein 1 (ECM1) is a protein
from Homo sapiens identified by UniProt accession
Q16610, 540 residues long.
MolForge cross-references it against 0 known binders and
277 disease associations.
Target properties
| Protein name | Extracellular matrix protein 1 |
|---|
| UniProt accession | Q16610 |
|---|
| Gene | ECM1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 540 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (277)
Diseases linked to this target (Open Targets).
- lipoid proteinosis · score 0.78
- extracellular matrix protein 1 measurement · score 0.28
- low density lipoprotein cholesterol measurement · score 0.27
- C-reactive protein measurement · score 0.25
- breast adenocarcinoma · score 0.25
- neutrophil count · score 0.22
- platelet count · score 0.20
- genetic disorder · score 0.19
- refractive error measurement · score 0.19
- serum alanine aminotransferase measurement · score 0.18
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q16610-F1 | alphafold | PREDICTED | 67.87 | — |
Amino-acid sequence (540 residues)
MGTTARAALV LTYLAVASAA SEGGFTATGQ RQLRPEHFQE VGYAAPPSPP LSRSLPMDHP DSSQHGPPFE GQSQVQPPPS QEATPLQQEK LLPAQLPAEK EVGPPLPQEA VPLQKELPSL QHPNEQKEGT PAPFGDQSHP EPESWNAAQH CQQDRSQGGW GHRLDGFPPG RPSPDNLNQI CLPNRQHVVY GPWNLPQSSY SHLTRQGETL NFLEIGYSRC CHCRSHTNRL ECAKLVWEEA MSRFCEAEFS VKTRPHWCCT RQGEARFSCF QEEAPQPHYQ LRACPSHQPD ISSGLELPFP PGVPTLDNIK NICHLRRFRS VPRNLPATDP LQRELLALIQ LEREFQRCCR QGNNHTCTWK AWEDTLDKYC DREYAVKTHH HLCCRHPPSP TRDECFARRA PYPNYDRDIL TIDIGRVTPN LMGHLCGNQR VLTKHKHIPG LIHNMTARCC DLPFPEQACC AEEEKLTFIN DLCGPRRNIW RDPALCCYLS PGDEQVNCFN INYLRNVALV SGDTENAKGQ GEQGSTGGTN ISSTSEPKEE
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