Neuronal regeneration-related protein (NREP)

About Neuronal regeneration-related protein

Neuronal regeneration-related protein (NREP) is a protein from Homo sapiens identified by UniProt accession Q16612, 68 residues long. MolForge cross-references it against 0 known binders and 123 disease associations.

Target properties

Protein name	Neuronal regeneration-related protein
UniProt accession	Q16612
Gene	NREP
Organism	Homo sapiens
Length	68 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (123)

Diseases linked to this target (Open Targets).

hematocrit · score 0.49
erythrocyte count · score 0.48
hemoglobin measurement · score 0.46
mean corpuscular volume · score 0.44
red blood cell density measurement · score 0.43
platelet count · score 0.42
lean body mass · score 0.41
total blood protein measurement · score 0.40
platelet crit · score 0.40
mean corpuscular hemoglobin · score 0.40

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q16612-F1	alphafold	PREDICTED	67.01	—

Amino-acid sequence (68 residues)

MVYYPELFVW VSQEPFPNKD MEGRLPKGRL PVPKEVNRKK NDETNAASLT PLGSSELRSP RISYLHFF

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards