About Protein NKG7
Protein NKG7 (NKG7) is a protein
from Homo sapiens identified by UniProt accession
Q16617, 165 residues long.
MolForge cross-references it against 0 known binders and
160 disease associations.
Target properties
| Protein name | Protein NKG7 |
|---|
| UniProt accession | Q16617 |
|---|
| Gene | NKG7 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 165 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (160)
Diseases linked to this target (Open Targets).
- neutrophil count · score 0.15
- neutrophil percentage of leukocytes · score 0.13
- sum of basophil and neutrophil counts · score 0.11
- neoplasm · score 0.09
- Blackfan-Diamond anemia · score 0.07
- granulocyte count · score 0.07
- lymphocyte percentage of leukocytes · score 0.07
- sum of neutrophil and eosinophil counts · score 0.07
- myeloid white cell count · score 0.07
- hereditary persistence of fetal hemoglobin-sickle cell disease syndrome · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q16617-F1 | alphafold | PREDICTED | 87.08 | — |
Amino-acid sequence (165 residues)
MELCRSLALL GGSLGLMFCL IALSTDFWFE AVGPTHSAHS GLWPTGHGDI ISGYIHVTQT FSIMAVLWAL VSVSFLVLSC FPSLFPPGHG PLVSTTAAFA AAISMVVAMA VYTSERWDQP PHPQIQTFFS WSFYLGWVSA ILLLCTGALS LGAHCGGPRP GYETL
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