About Cardiotrophin-1
Cardiotrophin-1 (CTF1) is a protein
from Homo sapiens identified by UniProt accession
Q16619, 201 residues long.
MolForge cross-references it against 0 known binders and
191 disease associations.
Target properties
| Protein name | Cardiotrophin-1 |
|---|
| UniProt accession | Q16619 |
|---|
| Gene | CTF1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 201 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (191)
Diseases linked to this target (Open Targets).
- autosomal dominant dilated cardiomyopathy · score 0.20
- cardiomyopathy · score 0.18
- hypertrophic cardiomyopathy · score 0.13
- familial hypertrophic cardiomyopathy · score 0.12
- dilated cardiomyopathy · score 0.11
- cutaneous melanoma · score 0.10
- obstructive sleep apnea · score 0.09
- neoplasm · score 0.08
- serum non-albumin protein measurement · score 0.07
- amyotrophic lateral sclerosis · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q16619-F1 | alphafold | PREDICTED | 85.12 | — |
Amino-acid sequence (201 residues)
MSRREGSLED PQTDSSVSLL PHLEAKIRQT HSLAHLLTKY AEQLLQEYVQ LQGDPFGLPS FSPPRLPVAG LSAPAPSHAG LPVHERLRLD AAALAALPPL LDAVCRRQAE LNPRAPRLLR RLEDAARQAR ALGAAVEALL AALGAANRGP RAEPPAATAS AASATGVFPA KVLGLRVCGL YREWLSRTEG DLGQLLPGGS A
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