Male-enhanced antigen 1 (MEA1)

About Male-enhanced antigen 1

Male-enhanced antigen 1 (MEA1) is a protein from Homo sapiens identified by UniProt accession Q16626, 185 residues long. MolForge cross-references it against 0 known binders and 24 disease associations.

Target properties

Protein name	Male-enhanced antigen 1
UniProt accession	Q16626
Gene	MEA1
Organism	Homo sapiens
Length	185 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (24)

Diseases linked to this target (Open Targets).

Hogue-Janssens syndrome 1 · score 0.12
genetic disorder · score 0.12
body height · score 0.07
hemoglobin measurement · score 0.05
hematocrit · score 0.03
systemic juvenile idiopathic arthritis · score 0.02
lung adenocarcinoma · score 0.01
Abnormal sperm morphology · score 0.01
Alzheimer disease · score 0.01
echinococcosis · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q16626-F1	alphafold	PREDICTED	64.07	—

Amino-acid sequence (185 residues)

MGPERHLSGA PARMATVVLG GDTMGPERIF PNQTEELGHQ GPSEGTGDWS SEEPEEEQEE TGSGPAGYSY QPLNQDPEQE EVELAPVGDG DVVADIQDRI QALGLHLPDP PLESEDEDEE GATALNNHSS IPMDPEHVEL VKRTMAGVSL PAPGVPAWAR EISDAQWEDV VQKALQARQA SPAWK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards