C-C motif chemokine 14 (CCL14)

About C-C motif chemokine 14

C-C motif chemokine 14 (CCL14) is a protein from Homo sapiens identified by UniProt accession Q16627, 93 residues long. MolForge cross-references it against 0 known binders and 81 disease associations.

Target properties

Protein name	C-C motif chemokine 14
UniProt accession	Q16627
Gene	CCL14
Organism	Homo sapiens
Length	93 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (81)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.37
C-C motif chemokine 14 measurement · score 0.15
blood protein measurement · score 0.15
CCL23 measurement · score 0.14
C-C motif chemokine 3 measurement · score 0.13
C-C motif chemokine 18 measurement · score 0.13
C-C motif chemokine 23 measurement · score 0.13
acute kidney failure · score 0.10
neoplasm · score 0.10
hepatocellular carcinoma · score 0.10

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q16627-F1	alphafold	PREDICTED	85.41	—

Amino-acid sequence (93 residues)

MKISVAAIPF FLLITIALGT KTESSSRGPY HPSECCFTYT TYKIPRQRIM DYYETNSQCS KPGIVFITKR GHSVCTNPSD KWVQDYIKDM KEN

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards