Melanoma antigen recognized by T-cells 1 (MLANA)

About Melanoma antigen recognized by T-cells 1

Melanoma antigen recognized by T-cells 1 (MLANA) is a protein from Homo sapiens identified by UniProt accession Q16655, 118 residues long. MolForge cross-references it against 0 known binders and 272 disease associations.

Target properties

Protein name	Melanoma antigen recognized by T-cells 1
UniProt accession	Q16655
Gene	MLANA
Organism	Homo sapiens
Length	118 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (272)

Diseases linked to this target (Open Targets).

hair colour measurement · score 0.32
multiple sclerosis · score 0.25
asthma · score 0.22
hair color · score 0.19
skin pigmentation · score 0.17
melanoma · score 0.10
neoplasm · score 0.09
PHF-tau measurement · score 0.09
seasonal allergic rhinitis · score 0.08
Griscelli syndrome type 3 · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q16655-F1	alphafold	PREDICTED	63.92	—

Amino-acid sequence (118 residues)

MPREDAHFIY GYPKKGHGHS YTTAEEAAGI GILTVILGVL LLIGCWYCRR RNGYRALMDK SLHVGTQCAL TRRCPQEGFD HRDSKVSLQE KNCEPVVPNA PPAYEKLSAE QSPPPYSP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards