C-C motif chemokine 15 (CCL15)

About C-C motif chemokine 15

C-C motif chemokine 15 (CCL15) is a protein from Homo sapiens identified by UniProt accession Q16663, 113 residues long. MolForge cross-references it against 0 known binders and 144 disease associations.

Target properties

Protein name	C-C motif chemokine 15
UniProt accession	Q16663
Gene	CCL15
Organism	Homo sapiens
Length	113 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (144)

Diseases linked to this target (Open Targets).

blood protein measurement · score 0.29
neurodegenerative disease · score 0.29
C-C motif chemokine 15 measurement · score 0.22
CCL15 measurement · score 0.20
C-C motif chemokine 14 measurement · score 0.18
CCL23 measurement · score 0.17
cerebrospinal fluid biomarker measurement · score 0.12
hepatocellular carcinoma · score 0.10
protein measurement · score 0.10
fetal genotype effect measurement · score 0.09

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q16663-F1	alphafold	PREDICTED	77.99	—

Amino-acid sequence (113 residues)

MKVSVAALSC LMLVAVLGSQ AQFTNDAETE LMMSKLPLEN PVVLNSFHFA ADCCTSYISQ SIPCSLMKSY FETSSECSKP GVIFLTKKGR QVCAKPSGPG VQDCMKKLKP YSI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards