About Cyclin-dependent kinase inhibitor 3
Cyclin-dependent kinase inhibitor 3 (CDKN3) is a protein
from Homo sapiens identified by UniProt accession
Q16667, 212 residues long.
MolForge cross-references it against 0 known binders and
232 disease associations.
Target properties
| Protein name | Cyclin-dependent kinase inhibitor 3 |
|---|
| UniProt accession | Q16667 |
|---|
| Gene | CDKN3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 212 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (232)
Diseases linked to this target (Open Targets).
- Red cell distribution width · score 0.46
- cortical thickness · score 0.33
- refractive error · score 0.32
- reticulocyte measurement · score 0.29
- reticulocyte count · score 0.28
- cortical surface area measurement · score 0.27
- hepatocellular carcinoma · score 0.27
- brain measurement · score 0.26
- hepatocellular adenoma · score 0.25
- brain volume measurement · score 0.24
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q16667-F1 | alphafold | PREDICTED | 91.18 | — |
Amino-acid sequence (212 residues)
MKPPSSIQTS EFDSSDEEPI EDEQTPIHIS WLSLSRVNCS QFLGLCALPG CKFKDVRRNV QKDTEELKSC GIQDIFVFCT RGELSKYRVP NLLDLYQQCG IITHHHPIAD GGTPDIASCC EIMEELTTCL KNYRKTLIHC YGGLGRSCLV AACLLLYLSD TISPEQAIDS LRDLRGSGAI QTIKQYNYLH EFRDKLAAHL SSRDSQSRSV SR
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