About Zinc finger and SCAN domain-containing protein 26
Zinc finger and SCAN domain-containing protein 26 (ZSCAN26) is a protein
from Homo sapiens identified by UniProt accession
Q16670, 478 residues long.
MolForge cross-references it against 0 known binders and
87 disease associations.
Target properties
| Protein name | Zinc finger and SCAN domain-containing protein 26 |
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| UniProt accession | Q16670 |
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| Gene | ZSCAN26 |
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| Organism | Homo sapiens |
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| Length | 478 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (87)
Diseases linked to this target (Open Targets).
- reticulocyte count · score 0.17
- base metabolic rate measurement · score 0.16
- major depressive disorder · score 0.13
- stress-related disorder · score 0.10
- anxiety · score 0.10
- type 1 diabetes mellitus · score 0.10
- eosinophil count · score 0.08
- basophil count · score 0.07
- lymphocyte count · score 0.07
- pulse pressure measurement · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q16670-F1 | alphafold | PREDICTED | 63.39 | — |
Amino-acid sequence (478 residues)
MATALVSAHS LAPLNLKKEG LRVVREDHYS TWEQGFKLQG NSKGLGQEPL CKQFRQLRYE ETTGPREALS RLRELCQQWL QPETHTKEQI LELLVLEQFL IILPKELQAR VQEHHPESRE DVVVVLEDLQ LDLGETGQQD PDQPKKQKIL VEEMAPLKGV QEQQVRHECE VTKPEKEKGE ETRIENGKLI VVTDSCGRVE SSGKISEPME AHNEGSNLER HQAKPKEKIE YKCSEREQRF IQHLDLIEHA STHTGKKLCE SDVCQSSSLT GHKKVLSREK GHQCHECGKA FQRSSHLVRH QKIHLGEKPY QCNECGKVFS QNAGLLEHLR IHTGEKPYLC IHCGKNFRRS SHLNRHQRIH SQEEPCECKE CGKTFSQALL LTHHQRIHSH SKSHQCNECG KAFSLTSDLI RHHRIHTGEK PFKCNICQKA FRLNSHLAQH VRIHNEEKPY QCSECGEAFR QRSGLFQHQR YHHKDKLA
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