Melanoma-derived growth regulatory protein (MIA)

About Melanoma-derived growth regulatory protein

Melanoma-derived growth regulatory protein (MIA) is a protein from Homo sapiens identified by UniProt accession Q16674, 131 residues long. MolForge cross-references it against 0 known binders and 71 disease associations.

Target properties

Protein name	Melanoma-derived growth regulatory protein
UniProt accession	Q16674
Gene	MIA
Organism	Homo sapiens
Length	131 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (71)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.36
melanoma-derived growth regulatory protein measurement · score 0.24
blood protein measurement · score 0.20
erythrocyte count · score 0.16
protein measurement · score 0.16
alkaline phosphatase measurement · score 0.11
hematocrit · score 0.11
hemoglobin measurement · score 0.08
eosinophil count · score 0.08
neoplasm · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q16674-F1	alphafold	PREDICTED	86.38	—

Amino-acid sequence (131 residues)

MARSLVCLGV IILLSAFSGP GVRGGPMPKL ADRKLCADQE CSHPISMAVA LQDYMAPDCR FLTIHRGQVV YVFSKLKGRG RLFWGGSVQG DYYGDLAARL GYFPSSIVRE DQTLKPGKVD VKTDKWDFYC Q

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards