About Cytochrome P450 2A13
Cytochrome P450 2A13 (CYP2A13) is a protein
from Homo sapiens identified by UniProt accession
Q16696, 494 residues long.
MolForge cross-references it against 0 known binders and
32 disease associations.
Target properties
| Protein name | Cytochrome P450 2A13 |
|---|
| UniProt accession | Q16696 |
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| Gene | CYP2A13 |
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| Organism | Homo sapiens |
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| Length | 494 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
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Disease associations (32)
Diseases linked to this target (Open Targets).
- cutaneous melanoma · score 0.23
- glioblastoma multiforme · score 0.22
- lung adenocarcinoma · score 0.21
- endometrial cancer · score 0.16
- urinary bladder cancer · score 0.13
- head and neck squamous cell carcinoma · score 0.10
- neoplasm · score 0.04
- non-small cell lung carcinoma · score 0.03
- DDT metabolite measurement · score 0.02
- urinary bladder carcinoma · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q16696-F1 | alphafold | PREDICTED | 96.17 | — |
Amino-acid sequence (494 residues)
MLASGLLLVT LLACLTVMVL MSVWRQRKSR GKLPPGPTPL PFIGNYLQLN TEQMYNSLMK ISERYGPVFT IHLGPRRVVV LCGHDAVKEA LVDQAEEFSG RGEQATFDWL FKGYGVAFSN GERAKQLRRF SIATLRGFGV GKRGIEERIQ EEAGFLIDAL RGTHGANIDP TFFLSRTVSN VISSIVFGDR FDYEDKEFLS LLRMMLGSFQ FTATSTGQLY EMFSSVMKHL PGPQQQAFKE LQGLEDFIAK KVEHNQRTLD PNSPRDFIDS FLIRMQEEEK NPNTEFYLKN LVMTTLNLFF AGTETVSTTL RYGFLLLMKH PEVEAKVHEE IDRVIGKNRQ PKFEDRAKMP YTEAVIHEIQ RFGDMLPMGL AHRVNKDTKF RDFFLPKGTE VFPMLGSVLR DPRFFSNPRD FNPQHFLDKK GQFKKSDAFV PFSIGKRYCF GEGLARMELF LFFTTIMQNF RFKSPQSPKD IDVSPKHVGF ATIPRNYTMS FLPR
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