About Thiosulfate sulfurtransferase
Thiosulfate sulfurtransferase (TST) is a protein
from Homo sapiens identified by UniProt accession
Q16762, 297 residues long.
MolForge cross-references it against 0 known binders and
97 disease associations.
Target properties
| Protein name | Thiosulfate sulfurtransferase |
|---|
| UniProt accession | Q16762 |
|---|
| Gene | TST |
|---|
| Organism | Homo sapiens |
|---|
| Length | 297 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (97)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.36
- mean corpuscular hemoglobin · score 0.30
- mean corpuscular hemoglobin concentration · score 0.29
- protein measurement · score 0.22
- Red cell distribution width · score 0.12
- basophil count · score 0.09
- eosinophil count · score 0.09
- Crohn's disease · score 0.07
- erythrocyte count · score 0.07
- eye colour measurement · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q16762-F1 | alphafold | PREDICTED | 96.42 | — |
Amino-acid sequence (297 residues)
MVHQVLYRAL VSTKWLAESI RTGKLGPGLR VLDASWYSPG TREARKEYLE RHVPGASFFD IEECRDTASP YEMMLPSEAG FAEYVGRLGI SNHTHVVVYD GEHLGSFYAP RVWWMFRVFG HRTVSVLNGG FRNWLKEGHP VTSEPSRPEP AVFKATLDRS LLKTYEQVLE NLESKRFQLV DSRSQGRFLG TEPEPDAVGL DSGHIRGAVN MPFMDFLTED GFEKGPEELR ALFQTKKVDL SQPLIATCRK GVTACHVALA AYLCGKPDVA VYDGSWSEWF RRAPPESRVS QGKSEKA
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