Glutaminyl-peptide cyclotransferase (QPCT)

About Glutaminyl-peptide cyclotransferase

Glutaminyl-peptide cyclotransferase (QPCT) is a protein from Homo sapiens identified by UniProt accession Q16769, 361 residues long. MolForge cross-references it against 0 known binders and 136 disease associations.

Target properties

Protein name	Glutaminyl-peptide cyclotransferase
UniProt accession	Q16769
Gene	QPCT
Organism	Homo sapiens
Length	361 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q16769-F1	alphafold	PREDICTED	92.41	—

Amino-acid sequence (361 residues)

MAGGRHRRVV GTLHLLLLVA ALPWASRGVS PSASAWPEEK NYHQPAILNS SALRQIAEGT SISEMWQNDL QPLLIERYPG SPGSYAARQH IMQRIQRLQA DWVLEIDTFL SQTPYGYRSF SNIISTLNPT AKRHLVLACH YDSKYFSHWN NRVFVGATDS AVPCAMMLEL ARALDKKLLS LKTVSDSKPD LSLQLIFFDG EEAFLHWSPQ DSLYGSRHLA AKMASTPHPP GARGTSQLHG MDLLVLLDLI GAPNPTFPNF FPNSARWFER LQAIEHELHE LGLLKDHSLE GRYFQNYSYG GVIQDDHIPF LRRGVPVLHL IPSPFPEVWH TMDDNEENLD ESTIDNLNKI LQVFVLEYLH L

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards