About Glutathione S-transferase A3
Glutathione S-transferase A3 (GSTA3) is a protein
from Homo sapiens identified by UniProt accession
Q16772, 222 residues long.
MolForge cross-references it against 0 known binders and
68 disease associations.
Target properties
| Protein name | Glutathione S-transferase A3 |
|---|
| UniProt accession | Q16772 |
|---|
| Gene | GSTA3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 222 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (68)
Diseases linked to this target (Open Targets).
- neuroinflammatory disorder · score 0.30
- t-tau:beta-amyloid 1-42 ratio measurement · score 0.28
- protein measurement · score 0.15
- Hepatic fibrosis · score 0.04
- platelet count · score 0.03
- testosterone measurement · score 0.03
- Red cell distribution width · score 0.03
- high density lipoprotein cholesterol measurement · score 0.03
- platelet crit · score 0.02
- vitamin C measurement · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q16772-F1 | alphafold | PREDICTED | 97.43 | — |
Amino-acid sequence (222 residues)
MAGKPKLHYF NGRGRMEPIR WLLAAAGVEF EEKFIGSAED LGKLRNDGSL MFQQVPMVEI DGMKLVQTRA ILNYIASKYN LYGKDIKERA LIDMYTEGMA DLNEMILLLP LCRPEEKDAK IALIKEKTKS RYFPAFEKVL QSHGQDYLVG NKLSRADISL VELLYYVEEL DSSLISNFPL LKALKTRISN LPTVKKFLQP GSPRKPPADA KALEEARKIF RF
Explore Glutathione S-transferase A3 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets