Histone H2A type 2-C (H2AC20)

About Histone H2A type 2-C

Histone H2A type 2-C (H2AC20) is a protein from Homo sapiens identified by UniProt accession Q16777, 129 residues long. MolForge cross-references it against 0 known binders and 20 disease associations.

Target properties

Protein name	Histone H2A type 2-C
UniProt accession	Q16777
Gene	H2AC20
Organism	Homo sapiens
Length	129 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (20)

Diseases linked to this target (Open Targets).

viral disease · score 0.50
infectious disease · score 0.50
breast carcinoma · score 0.38
cancer · score 0.37
melanoma · score 0.37
actinic keratosis · score 0.05
sebaceous of Jadassohn nevus · score 0.05
squamous cell carcinoma · score 0.05
triglyceride measurement · score 0.04
bilirubin measurement · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q16777-F1	alphafold	PREDICTED	91.05	—

Amino-acid sequence (129 residues)

MSGRGKQGGK ARAKAKSRSS RAGLQFPVGR VHRLLRKGNY AERVGAGAPV YMAAVLEYLT AEILELAGNA ARDNKKTRII PRHLQLAIRN DEELNKLLGK VTIAQGGVLP NIQAVLLPKK TESHKAKSK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards