About Cysteine dioxygenase type 1
Cysteine dioxygenase type 1 (CDO1) is a protein
from Homo sapiens identified by UniProt accession
Q16878, 200 residues long.
MolForge cross-references it against 0 known binders and
129 disease associations.
Target properties
| Protein name | Cysteine dioxygenase type 1 |
| UniProt accession | Q16878 |
| Gene | CDO1 |
| Organism | Homo sapiens |
| Length | 200 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (129)
Diseases linked to this target (Open Targets).
- alkaline phosphatase measurement · score 0.36
- adolescent idiopathic scoliosis · score 0.25
- low density lipoprotein particle size measurement · score 0.21
- intraocular pressure measurement · score 0.17
- body height · score 0.17
- central corneal thickness · score 0.14
- forced expiratory volume · score 0.14
- vital capacity · score 0.13
- neoplasm · score 0.10
- BMI-adjusted hip circumference · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-Q16878-F1 | alphafold | PREDICTED | 93.60 | — |
Amino-acid sequence (200 residues)
MEQTEVLKPR TLADLIRILH QLFAGDEVNV EEVQAIMEAY ESDPTEWAMY AKFDQYRYTR NLVDQGNGKF NLMILCWGEG HGSSIHDHTN SHCFLKMLQG NLKETLFAWP DKKSNEMVKK SERVLRENQC AYINDSIGLH RVENISHTEP AVSLHLYSPP FDTCHAFDQR TGHKNKVTMT FHSKFGIRTP NATSGSLENN
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