About Tumor protein D53
Tumor protein D53 (TPD52L1) is a protein
from Homo sapiens identified by UniProt accession
Q16890, 204 residues long.
MolForge cross-references it against 0 known binders and
52 disease associations.
Target properties
| Protein name | Tumor protein D53 |
|---|
| UniProt accession | Q16890 |
|---|
| Gene | TPD52L1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 204 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (52)
Diseases linked to this target (Open Targets).
- urate measurement · score 0.33
- heel bone mineral density · score 0.33
- central nervous system disease · score 0.30
- mean reticulocyte volume · score 0.12
- isolated asymptomatic elevation of creatine phosphokinase · score 0.07
- neoplasm · score 0.05
- pentosuria · score 0.05
- balding measurement · score 0.04
- hemoglobin measurement · score 0.04
- erythrocyte count · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q16890-F1 | alphafold | PREDICTED | 64.63 | — |
Amino-acid sequence (204 residues)
MEAQAQGLLE TEPLQGTDED AVASADFSSM LSEEEKEELK AELVQLEDEI TTLRQVLSAK ERHLVEIKQK LGMNLMNELK QNFSKSWHDM QTTTAYKKTH ETLSHAGQKA TAAFSNVGTA ISKKFGDMSY SIRHSISMPA MRNSPTFKSF EERVETTVTS LKTKVGGTNP NGGSFEEVLS STAHASAQSL AGGSRRTKEE ELQC
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