About Deoxyribonuclease TATDN3
Deoxyribonuclease TATDN3 (TATDN3) is a protein
from Homo sapiens identified by UniProt accession
Q17R31, 274 residues long.
MolForge cross-references it against 0 known binders and
12 disease associations.
Target properties
| Protein name | Deoxyribonuclease TATDN3 |
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| UniProt accession | Q17R31 |
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| Gene | TATDN3 |
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| Organism | Homo sapiens |
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| Length | 274 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (12)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- eosinophil count · score 0.19
- childhood onset asthma · score 0.15
- platelet count · score 0.13
- type 1 diabetes mellitus · score 0.13
- eosinophil percentage of leukocytes · score 0.11
- drug use measurement · score 0.10
- melorheostosis · score 0.04
- osteoporosis · score 0.04
- Osteoporosis · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q17R31-F1 | alphafold | PREDICTED | 96.16 | — |
Amino-acid sequence (274 residues)
MRAAGVGLVD CHCHLSAPDF DRDLDDVLEK AKKANVVALV AVAEHSGEFE KIMQLSERYN GFVLPCLGVH PVQGLPPEDQ RSVTLKDLDV ALPIIENYKD RLLAIGEVGL DFSPRFAGTG EQKEEQRQVL IRQIQLAKRL NLPVNVHSRS AGRPTINLLQ EQGAEKVLLH AFDGRPSVAM EGVRAGYFFS IPPSIIRSGQ KQKLVKQLPL TSICLETDSP ALGPEKQVRN EPWNISISAE YIAQVKGISV EEVIEVTTQN ALKLFPKLRH LLQK
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