About Protein FAM187B
Protein FAM187B (FAM187B) is a protein
from Homo sapiens identified by UniProt accession
Q17R55, 369 residues long.
MolForge cross-references it against 0 known binders and
8 disease associations.
Target properties
| Protein name | Protein FAM187B |
|---|
| UniProt accession | Q17R55 |
|---|
| Gene | FAM187B |
|---|
| Organism | Homo sapiens |
|---|
| Length | 369 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (8)
Diseases linked to this target (Open Targets).
- bilirubin measurement · score 0.17
- reticulocyte count · score 0.15
- reticulocyte measurement · score 0.14
- Immature Reticulocyte Fraction Measurement · score 0.10
- Red cell distribution width · score 0.05
- monocyte count · score 0.02
- mean platelet volume · score 0.02
- neoplasm · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q17R55-F1 | alphafold | PREDICTED | 86.39 | — |
Amino-acid sequence (369 residues)
MPPMLWLLLH FAAPALGFYF SISCPSGKQC QQALLSGNDI LLYCNSSGAH WYYLFTQGKK GRLTSLTNIS NMEIMPEGSL LIKDPLPSQT GLYHCWNKNG RQVVQYEIDF QDVTTLHITH KDLGQRPLQN ETLHLGSKQL IFTWWEPWQD CNRCEEPGEC KRLGYRYIEE PLEEAMPCWL YLGEVLVWSS RLRPELQVEA CHVQCTNNTQ LRVDYVIFDN FRLDEKTEFV WLDCPLGSMY RPVNWRANDT PLTWESQLSG QDFTTFLDPS TGGRQLQVFQ PAVYKCFVQQ ELVAQFKPAA SLETLEAQWR ENDAQWREAR KALRGRADSV LKGLKLVLLV VTVLALLGAL LKCIHPSPGR RSTQVLVVK
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