Retrotransposon Gag-like protein 8B (RTL8B)

About Retrotransposon Gag-like protein 8B

Retrotransposon Gag-like protein 8B (RTL8B) is a protein from Homo sapiens identified by UniProt accession Q17RB0, 113 residues long. MolForge cross-references it against 0 known binders and 2 disease associations.

Target properties

Protein name	Retrotransposon Gag-like protein 8B
UniProt accession	Q17RB0
Gene	RTL8B
Organism	Homo sapiens
Length	113 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (2)

Diseases linked to this target (Open Targets).

colorectal cancer · score 0.01
fetal growth restriction · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q17RB0-F1	alphafold	PREDICTED	89.42	—

Amino-acid sequence (113 residues)

MEGRVQLMKA LLARPLRPAA RRWRNPIPFP ETFDGDTDRL PEFIVQTSSY MFVDENTFSN DALKVTFLIT RLTGPALQWV IPYIKKESPL LSDYRGFLAE MKRVFGWEED EDF

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards