About Odontogenesis associated phosphoprotein
Odontogenesis associated phosphoprotein (ODAPH) is a protein
from Homo sapiens identified by UniProt accession
Q17RF5, 130 residues long.
MolForge cross-references it against 0 known binders and
100 disease associations.
Target properties
| Protein name | Odontogenesis associated phosphoprotein |
|---|
| UniProt accession | Q17RF5 |
|---|
| Gene | ODAPH |
|---|
| Organism | Homo sapiens |
|---|
| Length | 130 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (100)
Diseases linked to this target (Open Targets).
- amelogenesis imperfecta hypomaturation type 2A4 · score 0.62
- Hypomaturation amelogenesis imperfecta · score 0.51
- serum alanine aminotransferase measurement · score 0.16
- Hypoplastic amelogenesis imperfecta · score 0.09
- FEV/FVC ratio · score 0.09
- platelet count · score 0.08
- dentin dysplasia type I · score 0.08
- amelogenesis imperfecta · score 0.07
- amelogenesis imperfecta, type ij · score 0.07
- amelogenesis imperfecta, IIa 1K · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q17RF5-F1 | alphafold | PREDICTED | 61.72 | — |
Amino-acid sequence (130 residues)
MARRHCFSYW LLVCWLVVTV AEGQEEVFTP PGDSQNNADA TDCQIFTLTP PPAPRSPVTR AQPITKTPRC PFHFFPRRPR IHFRFPNRPF VPSRCNHRFP FQPFYWPHRY LTYRYFPRRR LQRGSSSEES
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