Protein FAM98C (FAM98C)

About Protein FAM98C

Protein FAM98C (FAM98C) is a protein from Homo sapiens identified by UniProt accession Q17RN3, 349 residues long. MolForge cross-references it against 0 known binders and 9 disease associations.

Target properties

Protein name	Protein FAM98C
UniProt accession	Q17RN3
Gene	FAM98C
Organism	Homo sapiens
Length	349 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (9)

Diseases linked to this target (Open Targets).

autism spectrum disorder · score 0.26
asphyxiating thoracic dystrophy 3 · score 0.26
short rib-polydactyly syndrome, Majewski type · score 0.26
Short rib-polydactyly syndrome, Verma-Naumoff type · score 0.26
eosinophil count · score 0.06
D dimer measurement · score 0.05
eosinophil percentage of leukocytes · score 0.04
basophil count · score 0.03
neutrophil percentage of granulocytes · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q17RN3-F1	alphafold	PREDICTED	79.20	—

Amino-acid sequence (349 residues)

MEAVKAEAWE GAAVAQDLLA LGYGGVPGAA SRGASCPDFR GLCVRLAAEL ATLGALEQQR EAGAEVLSAG DGPGAEEDFL RQLGSLLREL HCPDRALCGG DGAAALREPG AGLRLLRFLC SELQATRLLC LRSLLDPSPR PPLGEGVVEG AGMVQELDLT LQALGLPRPA PGTPASQLLQ ELHAKISELQ PSLPPGSLQP LLSCSLDAPR WEALESLSQS LRDQYRCRRC LLLKRLDLTT SAFHWSDRAE AQGEAMRAVL IPIREVLTPE SDISIAHVLA ARADLSCLVP ATSVAVRRGT CCAINKVLMG NVPDRGGRPN ELEPPMPTWR SRREDGGPQC WGRKKKKKK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards