About NTPase KAP family P-loop domain-containing protein 1
NTPase KAP family P-loop domain-containing protein 1 (NKPD1) is a protein
from Homo sapiens identified by UniProt accession
Q17RQ9, 610 residues long.
MolForge cross-references it against 0 known binders and
12 disease associations.
Target properties
| Protein name | NTPase KAP family P-loop domain-containing protein 1 |
|---|
| UniProt accession | Q17RQ9 |
|---|
| Gene | NKPD1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 610 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (12)
Diseases linked to this target (Open Targets).
- apolipoprotein B measurement · score 0.46
- low density lipoprotein cholesterol measurement · score 0.25
- alkaline phosphatase measurement · score 0.19
- mean corpuscular volume · score 0.17
- total cholesterol measurement · score 0.14
- beta-amyloid 1-42 measurement · score 0.07
- adolescent idiopathic scoliosis · score 0.05
- monocyte percentage of leukocytes · score 0.02
- ichthyosis, lamellar, autosomal dominant · score 0.01
- cancer · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q17RQ9-F1 | alphafold | PREDICTED | 70.77 | — |
Amino-acid sequence (610 residues)
MQQEAAQRES EELQHVQWRP RAVSGWGVPQ LLWYLVFLQP IITEVHLRRR NVQFLFIRFS AWQYAGTDKL WAGLVTTLCE GIRRHYGALP FSVYSVLGNK PATRQDCCQS EWHCRRRVCL GLLALLAALG LGVGLLYLSL GGHALGHGSP SGSLLKVFGG AATTLSGSGL LMAVYSVGKH LFVSQRKKIE RLVSREKFGS QLGFMCEVKK EVELLTDFLC FLEIYQRRRL RVVLEVTGLD TCYPERVVGV LNAINTLLSD SHAPFIFILV VDPSILAACL ESAGNMKGTA DNGYLFLNRT VTLPFSVPIM GRRTKLQFLH DAVQSRDDLL YREMTRKPWL PGDAGGESAQ LLAVQAQAGT ERGQGRIDDE AARRIQEALF CLHDERDCLY EYVPDNVVSM RRIVNTVPIT VRLLQQQQQQ GDFGGPTPRQ AVAWVVLANQ WPCRLSWALQ CLEDRQQTGG APEGRARLWD VFRDNSRELH TMTKALQNVL DLDGDPELFE RFLGADFPFT VAEAQSLLRC TVNLDHSIRR RMGLIRAVSA LKPPSPPKSP TRDTPHAAHR ANSASRAPPS GRASGQAGEG HHTGDLAHRG KLWPVACALF RPGQSSPGGP
Explore NTPase KAP family P-loop domain-containing protein 1 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets