Pancreatic lipase-related protein 3 (PNLIPRP3)

About Pancreatic lipase-related protein 3

Pancreatic lipase-related protein 3 (PNLIPRP3) is a protein from Homo sapiens identified by UniProt accession Q17RR3, 467 residues long. MolForge cross-references it against 0 known binders and 16 disease associations.

Target properties

Protein name	Pancreatic lipase-related protein 3
UniProt accession	Q17RR3
Gene	PNLIPRP3
Organism	Homo sapiens
Length	467 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (16)

Diseases linked to this target (Open Targets).

genetic disorder · score 0.12
lung adenocarcinoma · score 0.11
cutaneous melanoma · score 0.11
esophageal cancer · score 0.10
squamous cell lung carcinoma · score 0.10
esophageal squamous cell carcinoma · score 0.04
hepatocellular carcinoma · score 0.01
dysplasia · score 0.01
rosacea · score 0.01
acne · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q17RR3-F1	alphafold	PREDICTED	89.27	—

Amino-acid sequence (467 residues)

MLGIWIVAFL FFGTSRGKEV CYERLGCFKD GLPWTRTFST ELVGLPWSPE KINTRFLLYT IHNPNAYQEI SAVNSSTIQA SYFGTDKITR INIAGWKTDG KWQRDMCNVL LQLEDINCIN LDWINGSREY IHAVNNLRVV GAEVAYFIDV LMKKFEYSPS KVHLIGHSLG AHLAGEAGSR IPGLGRITGL DPAGPFFHNT PKEVRLDPSD ANFVDVIHTN AARILFELGV GTIDACGHLD FYPNGGKHMP GCEDLITPLL KFNFNAYKKE MASFFDCNHA RSYQFYAESI LNPDAFIAYP CRSYTSFKAG NCFFCSKEGC PTMGHFADRF HFKNMKTNGS HYFLNTGSLS PFARWRHKLS VKLSGSEVTQ GTVFLRVGGA VRKTGEFAIV SGKLEPGMTY TKLIDADVNV GNITSVQFIW KKHLFEDSQN KLGAEMVINT SGKYGYKSTF CSQDIMGPNI LQNLKPC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards