Zinc finger SWIM domain-containing protein 7 (ZSWIM7)

About Zinc finger SWIM domain-containing protein 7

Zinc finger SWIM domain-containing protein 7 (ZSWIM7) is a protein from Homo sapiens identified by UniProt accession Q19AV6, 140 residues long. MolForge cross-references it against 0 known binders and 165 disease associations.

Target properties

Protein name	Zinc finger SWIM domain-containing protein 7
UniProt accession	Q19AV6
Gene	ZSWIM7
Organism	Homo sapiens
Length	140 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (165)

Diseases linked to this target (Open Targets).

ovarian dysgenesis 10 · score 0.44
46,XX gonadal dysgenesis · score 0.38
azoospermia · score 0.35
infertility · score 0.26
genetic disorder · score 0.18
mitochondrial complex III deficiency nuclear type 1 · score 0.18
bilirubin measurement · score 0.17
body mass index · score 0.15
vital capacity · score 0.15
lean body mass · score 0.15

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q19AV6-F1	alphafold	PREDICTED	92.16	—

Amino-acid sequence (140 residues)

MAVVLPAVVE ELLSEMAAAV QESARIPDEY LLSLKFLFGS SATQALDLVD RQSITLISSP SGRRVYQVLG SSSKTYTCLA SCHYCSCPAF AFSVLRKSDS ILCKHLLAVY LSQVMRTCQQ LSVSDKQLTD ILLMEKKQEA

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards