Endothelial cell-specific chemotaxis regulator (ECSCR)

About Endothelial cell-specific chemotaxis regulator

Endothelial cell-specific chemotaxis regulator (ECSCR) is a protein from Homo sapiens identified by UniProt accession Q19T08, 205 residues long. MolForge cross-references it against 0 known binders and 36 disease associations.

Target properties

Protein name	Endothelial cell-specific chemotaxis regulator
UniProt accession	Q19T08
Gene	ECSCR
Organism	Homo sapiens
Length	205 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (36)

Diseases linked to this target (Open Targets).

heart function measurement · score 0.12
alcohol consumption measurement · score 0.09
cholesterol-ester transfer protein deficiency · score 0.05
hypertriglyceridemia 2 · score 0.05
Hyperlipoproteinemia type 1 · score 0.05
hyperlipidemia due to hepatic triglyceride lipase deficiency · score 0.05
hypoalphalipoproteinemia, primary, 1 · score 0.05
Fish-eye disease · score 0.05
Combined hyperlipidemia · score 0.04
homozygous familial hypercholesterolemia · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q19T08-F1	alphafold	PREDICTED	56.48	—

Amino-acid sequence (205 residues)

MGTAGAMQLC WVILGFLLFR GHNSQPTMTQ TSSSQGGLGG LSLTTEPVSS NPGYIPSSEA NRPSHLSSTG TPGAGVPSSG RDGGTSRDTF QTVPPNSTTM SLSMREDATI LPSPTSETVL TVAAFGVISF IVILVVVVII LVGVVSLRFK CRKSKESEDP QKPGSSGLSE SCSTANGEKD SITLISMKNI NMNNGKQSLS AEKVL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards