About Sodium-coupled monocarboxylate transporter 2
Sodium-coupled monocarboxylate transporter 2 (SLC5A12) is a protein
from Homo sapiens identified by UniProt accession
Q1EHB4, 618 residues long.
MolForge cross-references it against 0 known binders and
32 disease associations.
Target properties
| Protein name | Sodium-coupled monocarboxylate transporter 2 |
|---|
| UniProt accession | Q1EHB4 |
|---|
| Gene | SLC5A12 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 618 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (32)
Diseases linked to this target (Open Targets).
- cutaneous melanoma · score 0.12
- body height · score 0.09
- Rheumatoid arthritis · score 0.06
- Crohn's disease · score 0.06
- non-small cell lung carcinoma · score 0.04
- blood protein measurement · score 0.04
- esophageal adenocarcinoma · score 0.03
- clear cell renal carcinoma · score 0.02
- head and neck squamous cell carcinoma · score 0.02
- Abnormality of refraction · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q1EHB4-F1 | alphafold | PREDICTED | 85.03 | — |
Amino-acid sequence (618 residues)
MEVKNFAVWD YVVFAALFFI SSGIGVFFAI KERKKATSRE FLVGGRQMSF GPVGLSLTAS FMSAVTVLGT PSEVYRFGAS FLVFFIAYLF VILLTSELFL PVFYRSGITS TYEYLQLRFN KPVRYAATVI YIVQTILYTG VVVYAPALAL NQVTGFDLWG SVFATGIVCT FYCTLGGLKA VVWTDAFQMV VMIVGFLTVL IQGSTHAGGF HNVLEQSTNG SRLHIFDFDV DPLRRHTFWT ITVGGTFTWL GIYGVNQSTI QRCISCKTEK HAKLALYFNL LGLWIILVCA VFSGLIMYSH FKDCDPWTSG IISAPDQLMP YFVMEIFATM PGLPGLFVAC AFSGTLSTVA SSINALATVT FEDFVKSCFP HLSDKLSTWI SKGLCLLFGV MCTSMAVAAS VMGGVVQASL SIHGMCGGPM LGLFSLGIVF PFVNWKGALG GLLTGITLSF WVAIGAFIYP APASKTWPLP LSTDQCIKSN VTATGPPVLS SRPGIADTWY SISYLYYSAV GCLGCIVAGV IISLITGRQR GEDIQPLLIR PVCNLFCFWS KKYKTLCWCG VQHDSGTEQE NLENGSARKQ GAESVLQNGL RRESLVHVPG YDPKDKSYNN MAFETTHF
Explore Sodium-coupled monocarboxylate transporter 2 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets