About Protein CLEC16A
Protein CLEC16A (CLEC16A) is a protein
from Homo sapiens identified by UniProt accession
Q2KHT3, 1053 residues long.
MolForge cross-references it against 0 known binders and
102 disease associations.
Target properties
| Protein name | Protein CLEC16A |
|---|
| UniProt accession | Q2KHT3 |
|---|
| Gene | CLEC16A |
|---|
| Organism | Homo sapiens |
|---|
| Length | 1053 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (102)
Diseases linked to this target (Open Targets).
- type 1 diabetes mellitus · score 0.45
- eosinophil count · score 0.36
- primary biliary cirrhosis · score 0.31
- asthma · score 0.30
- systemic lupus erythematosus · score 0.28
- eosinophil percentage of leukocytes · score 0.28
- multiple sclerosis · score 0.27
- lymphocyte count · score 0.27
- atopic eczema · score 0.26
- allergic rhinitis · score 0.26
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q2KHT3-F1 | alphafold | PREDICTED | 70.78 | — |
Amino-acid sequence (1053 residues)
MFGRSRSWVG GGHGKTSRNI HSLDHLKYLY HVLTKNTTVT EQNRNLLVET IRSITEILIW GDQNDSSVFD FFLEKNMFVF FLNILRQKSG RYVCVQLLQT LNILFENISH ETSLYYLLSN NYVNSIIVHK FDFSDEEIMA YYISFLKTLS LKLNNHTVHF FYNEHTNDFA LYTEAIKFFN HPESMVRIAV RTITLNVYKV SLDNQAMLHY IRDKTAVPYF SNLVWFIGSH VIELDDCVQT DEEHRNRGKL SDLVAEHLDH LHYLNDILII NCEFLNDVLT DHLLNRLFLP LYVYSLENQD KGGERPKISL PVSLYLLSQV FLIIHHAPLV NSLAEVILNG DLSEMYAKTE QDIQRSSAKP SIRCFIKPTE TLERSLEMNK HKGKRRVQKR PNYKNVGEEE DEEKGPTEDA QEDAEKAKGT EGGSKGIKTS GESEEIEMVI MERSKLSELA ASTSVQEQNT TDEEKSAAAT CSESTQWSRP FLDMVYHALD SPDDDYHALF VLCLLYAMSH NKGMDPEKLE RIQLPVPNAA EKTTYNHPLA ERLIRIMNNA AQPDGKIRLA TLELSCLLLK QQVLMSAGCI MKDVHLACLE GAREESVHLV RHFYKGEDIF LDMFEDEYRS MTMKPMNVEY LMMDASILLP PTGTPLTGID FVKRLPCGDV EKTRRAIRVF FMLRSLSLQL RGEPETQLPL TREEDLIKTD DVLDLNNSDL IACTVITKDG GMVQRFLAVD IYQMSLVEPD VSRLGWGVVK FAGLLQDMQV TGVEDDSRAL NITIHKPASS PHSKPFPILQ ATFIFSDHIR CIIAKQRLAK GRIQARRMKM QRIAALLDLP IQPTTEVLGF GLGSSTSTQH LPFRFYDQGR RGSSDPTVQR SVFASVDKVP GFAVAQCINQ HSSPSLSSQS PPSASGSPSG SGSTSHCDSG GTSSSSTPST AQSPADAPMS PELPKPHLPD QLVIVNETEA DSKPSKNVAR SAAVETASLS PSLVPARQPT ISLLCEDTAD TLSVESLTLV PPVDPHSLRS LTGMPPLSTP AAACTEPVGE EAACAEPVGT AED
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