About Kinesin-like protein KIF26B
Kinesin-like protein KIF26B (KIF26B) is a protein
from Homo sapiens identified by UniProt accession
Q2KJY2, 2108 residues long.
MolForge cross-references it against 0 known binders and
118 disease associations.
Target properties
| Protein name | Kinesin-like protein KIF26B |
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| UniProt accession | Q2KJY2 |
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| Gene | KIF26B |
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| Organism | Homo sapiens |
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| Length | 2108 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (118)
Diseases linked to this target (Open Targets).
- autosomal dominant cerebellar ataxia · score 0.38
- creatinine measurement · score 0.38
- brain measurement · score 0.35
- cortical surface area measurement · score 0.35
- neuroimaging measurement · score 0.35
- abortion · score 0.31
- cystatin C measurement · score 0.29
- osteoarthritis · score 0.29
- brain volume measurement · score 0.28
- venous thromboembolism · score 0.28
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q2KJY2-F1 | alphafold | PREDICTED | 45.19 | — |
Amino-acid sequence (2108 residues)
MNSVAGNKER LAVSTRGKKY GVNEVCSPTK PAAPFSPESW YRKAYEESRA GSRPTPEGAG SALGSSGTPS PGSGTSSPSS FTGSPGPASP GIGTSSPGSL GGSPGFGTGS PGSGSGGGSS PGSDRGVWCE NCNARLVELK RQALRLLLPG PFPGKDPAFS AVIHDKLQVP NTIRKAWNDR DNRCDICATH LNQLKQEAIQ MVLTLEQAAG SEHYDASPCS PPPLSNIPTL VGSRHVGGLQ QPRDWAFVPA PCATSNYTGF ANKHGSKPSS LGVSNGAEKK SGSPTHQAKV SLQMATSPSN GNILNSVAIQ AHQYLDGTWS LSRTNGVTLY PYQISQLMTE SSREGLTEAV LNRYNADKPS ACSVPASQGS CVASETSTGT SVAASFFARA AQKLNLSSKK KKHRPSTSSA AEPPLFATSF SGILQTSPPP APPCLLRAVN KVKDTPGLGK VKVMLRICST LARDTSESSS FLKVDPRKKQ ITLYDPLTCG GQNAFQKRGN QVPPKMFAFD AVFPQDASQA EVCAGTVAEV IQSVVNGADG CVFCFGHAKL GKSYTMIGKD DSMQNLGIIP CAISWLFKLI NERKEKTGAR FSVRVSAVEV WGKEENLRDL LSEVATGSLQ DGQSPGVYLC EDPICGTQLQ NQSELRAPTA EKAAFFLDAA IASRRSHQQD CDEDDHRNSH VFFTLHIYQY RMEKSGKGGM SGGRSRLHLI DLGSCVKALS KNREGGSGLC LSLSALGNVI LALVNGSKHI PYKESKLAML LRESLGNMNC RTTMIAHISA AVGSYAETLS TIQIASRVLR MKKKKTKYTS SSSGGESSCE EGRMRRPTQL RPFHTRATVD PDFPIAHLSS DPDYSSSSEQ SCDTVIYIGP NGTALSDKEL TDNEGPPDFV PIVPALQKTR GDSRPAEAGE AAAGKSERDC LKCNTFAELQ ERLDCIDGSE EPSSFPFEEL PAQFGPEQAS RGPRLSQAAG ASPLSESDKE DNGSEGQLTN REGPELPASK MQRSHSPVPA AAPAHSPSPA SPRSVPGSSS QHSASPLVQS PSLQSSRESL NSCGFVEGKP RPMGSPRLGI ASLSKTSEYK PPSSPSQRCK VYTQKGVLPS PAPLPPSSKD SGVASRESLL QPEVRTPPVG MSPQVLKKSM SAGSEGFPET PVDDEQQAAT PSESKKEILS TTMVTVQQPL ELNGEDELVF TLVEELTISG VLDSGRPTSI ISFNSDCSAR ALASGSRPVS IISSISEDLE CYSSTAPVSE VSITQFLPLP KMSLDEKAQD AGSRRSSISS WLSEMSAGSE GEQSCHSFIA QTCFGHGEAM AEPVASEFVS SLQNTAVVCR EKPKASPDNL LILSEMGDDS FNKAAPIKGC KISTVSKAMV TISNTANLSS CEGYIPMKTN ITVYPCIAMS PRNIQEPEAP TATPKAGPTL AQSRESKENS AKKEMKFEDP WLKREEEVKK ETAHPNEEGM MRCETATGPS NAETRAEQEQ DGKPSPGDRL SSSSGEVSAS PVTDNFRRVV DGCEMALPGL ATQSPVHPNK SVKSSSLPRA FQKASRQEEP DSLSYYCAAE TNGVGAASGT PPSKATLEGK VASPKHCVLA RPKGTPPLPP VRKSSLDQKN RASPQHSASG SGTSSPLNQP AAFPAGLPDE PSGKTKDASS SSKLFSAKLE QLASRSNSLG RATVSHYECL SLERAESLSS VSSRLHAGKD GTMPRAGRSL GRSAGTSPPS SGASPKAGQS KISAVSRLLL ASPRARGPSA STTKTLSFST KSLPQAVGQG SSSPPGGKHT PWSTQSLSRN RSSGLASKLP LRAVSGRISE LLQGGAGARG LQLRAGPEAE ARGGALAEDE PAAAHLLPSP YSKITPPRRP HRCSSGHGSD NSSVLSGELP PAMGKTALFY HSGGSSGYES VMRDSEATGS ASSAQDSTSE NSSSVGGRCR SLKTPKKRSN PGSQRRRLIP ALSLDTSSPV RKPPNSTGVR WVDGPLRSSP RGLGEPFEIK VYEIDDVERL QRRRGGASKE AMCFNAKLKI LEHRQQRIAE VRAKYEWLMK ELEATKQYLM LDPNKWLSEF DLEQVWELDS LEYLEALECV TERLESRVNF CKAHLMMITC FDITSRRR
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