Zinc finger protein 630 (ZNF630)

About Zinc finger protein 630

Zinc finger protein 630 (ZNF630) is a protein from Homo sapiens identified by UniProt accession Q2M218, 657 residues long. MolForge cross-references it against 0 known binders and 5 disease associations.

Target properties

Protein name	Zinc finger protein 630
UniProt accession	Q2M218
Gene	ZNF630
Organism	Homo sapiens
Length	657 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (5)

Diseases linked to this target (Open Targets).

Down syndrome · score 0.03
Intellectual disability · score 0.01
glioblastoma multiforme · score 0.00
cancer · score 0.00
pontocerebellar hypoplasia · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q2M218-F1	alphafold	PREDICTED	67.83	—

Amino-acid sequence (657 residues)

MIESQEPVTF EDVAVDFTQE EWQQLNPAQK TLHRDVMLET YNHLVSVGCS GIKPDVIFKL EHGKDPWIIE SELSRWIYPD RVKGLESSQQ IISGELLFQR EILERAPKDN SLYSVLKIWH IDNQMDRYQG NQDRVLRQVT VISRETLTDE MGSKYSAFGK MFNRCTDLAP LSQKFHKFDS CENSLKSNSD LLNYNRSYAR KNPTKRFRCG RPPKYNASCS VPEKEGFIHT GMEPYGDSQC EKVLSHKQAH VQYKKFQARE KPNVCSMCGK AFIKKSQLII HQRIHTGEKP YVCGDCRKAF SEKSHLIVHQ RIHTGEKPYE CTKYGRAFSR KSPFTVHQRV HTGEKPYECF ECPKAFSQKS HLIIHQRVHT REKPFECSEC RKAFCEMSHL FIHQITHTGK KPYECTECGK TFPRKTQLII HQRTHTGEKP YKCGECGKTF CQQSHLIGHQ RIHTGEKPYV CTDCGKAFSQ KSHLTGHQRL HTGEKPYMCT ECGKSFSQKS PLIIHQRIHT GEKPYQCGEC GKTFSQKSLL IIHLRVHTGE KPYECTECGR AFSLKSHLIL HQRGHTGEKP YECSECGKAF CGKSPLIIHQ KTHPREKTPE CAESGMTFFW KSQMITYQRR HTGEKPSRCS DCGKAFCQHV YFTGHQNPYR KDTLYIC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards