UPF0450 protein C17orf58 (C17orf58)

About UPF0450 protein C17orf58

UPF0450 protein C17orf58 (C17orf58) is a protein from Homo sapiens identified by UniProt accession Q2M2W7, 339 residues long. MolForge cross-references it against 0 known binders and 59 disease associations.

Target properties

Protein name	UPF0450 protein C17orf58
UniProt accession	Q2M2W7
Gene	C17orf58
Organism	Homo sapiens
Length	339 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (59)

Diseases linked to this target (Open Targets).

brain measurement · score 0.27
age at first sexual intercourse measurement · score 0.21
pulse pressure measurement · score 0.21
eosinophil count · score 0.18
body height · score 0.18
body mass index · score 0.18
cortical surface area measurement · score 0.17
cortical thickness · score 0.17
lean body mass · score 0.16
lung adenocarcinoma · score 0.16

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q2M2W7-F1	alphafold	PREDICTED	64.41	—

Amino-acid sequence (339 residues)

MTARAFWLLC LIVGSSPEAP VAERKTSPPH SRKPDSRGCP SAEETPGPRA QPLLEAPQRP RAAEVAPAAR AWPDPRRRKP PPPADNQASF REAARAPAGP PGPRLAQAEN RASPRREPAS EDAPRRARSR ALRFPAARPP ALATEGSAGH AHPNRPRAAA LAPGPAPAPP PRFSLSFGLS PPQRDAEPGA EPCARACRSD LDEREAFCES EFAVNGIVHD VDVLGAGIRL VTLLVDRDGL YKMNRLYLTP DGFFFRVHML ALDSSSCNKP CPEFKPGSRY IVMGHIYHKR RQLPTALLQV LRGRLRPGDG LLRSSSSYVK RFNRKREGQI QGAIHTQCI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards