About Protein Shroom1
Protein Shroom1 (SHROOM1) is a protein
from Homo sapiens identified by UniProt accession
Q2M3G4, 852 residues long.
MolForge cross-references it against 0 known binders and
25 disease associations.
Target properties
| Protein name | Protein Shroom1 |
|---|
| UniProt accession | Q2M3G4 |
|---|
| Gene | SHROOM1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 852 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (25)
Diseases linked to this target (Open Targets).
- Alzheimer disease · score 0.32
- Parkinson disease · score 0.32
- multiple sclerosis · score 0.32
- lysosomal storage disease · score 0.32
- neurodegenerative disease · score 0.32
- serum gamma-glutamyl transferase measurement · score 0.06
- lean body mass · score 0.04
- eosinophil count · score 0.03
- IGF-1 measurement · score 0.03
- monocyte percentage of leukocytes · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q2M3G4-F1 | alphafold | PREDICTED | 53.44 | — |
Amino-acid sequence (852 residues)
MEALGPGGDR ASPASSTSSL DLWHLSMRAD SAYSSFSAAS GGPEPRTQSP GTDLLPYLDW DYVRVVWGGP GPAPPDAALC TSPRPRPAVA ARSGPQPTEV PGTPGPLNRQ ATPLLYALAA EAEAAAQAAE PPSPPASRAA YRQRLQGAQR RVLRETSFQR KELRMSLPAR LRPTVPARPP ATHPRSASLS HPGGEGEPAR SRAPAPGTAG RGPLANQQRK WCFSEPGKLD RVGRGGGPAR ECLGEACSSS GLPGPEPLEF QHPALAKFED HEVGWLPETQ PQGSMNLDSG SLKLGDAFRP ASRSRSASGE VLGSWGGSGG TIPIVQAVPQ GAETPRPLFQ TKLSRFLPQK EAAVMYPAEL PQSSPADSEQ RVSETCIVPA WLPSLPDEVF LEEAPLVRMR SPPDPHASQG PPASVHASDQ PYGTGLGQRT GQVTVPTEYP LHECPGTAGA DDCWQGVNGS VGISRPTSHT PTGTANDNIP TIDPTGLTTN PPTAAESDLL KPVPADALGL SGNDTPGPSH NTALARGTGQ PGSRPTWPSQ CLEELVQELA RLDPSLCDPL ASQPSPEPPL GLLDGLIPLA EVRAAMRPAC GEAGEEAAST FEPGSYQFSF TQLLPAPREE TRLENPATHP VLDQPCGQGL PAPNNSIQGK KVELAARLQK MLQDLHTEQE RLQGEAQAWA RRQAALEAAV RQACAPQELE RFSRFMADLE RVLGLLLLLG SRLARVRRAL ARAASDSDPD EQASLLQRLR LLQRQEEDAK ELKEHVARRE RAVREVLVRA LPVEELRVYC ALLAGKAAVL AQQRNLDERI RLLQDQLDAI RDDLGHHAPS PSPARPPGTC PPVQPPFPLL LT
Explore Protein Shroom1 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets