About Ribulose-phosphate 3-epimerase-like protein 1
Ribulose-phosphate 3-epimerase-like protein 1 (RPEL1) is a protein
from Homo sapiens identified by UniProt accession
Q2QD12, 228 residues long.
MolForge cross-references it against 0 known binders and
48 disease associations.
Target properties
| Protein name | Ribulose-phosphate 3-epimerase-like protein 1 |
|---|
| UniProt accession | Q2QD12 |
|---|
| Gene | RPEL1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 228 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (48)
Diseases linked to this target (Open Targets).
- hypertension · score 0.08
- mean corpuscular volume · score 0.08
- diastolic blood pressure · score 0.08
- systolic blood pressure · score 0.07
- blood pressure · score 0.06
- birth weight · score 0.06
- protein measurement · score 0.05
- cortical surface area measurement · score 0.05
- pulse pressure measurement · score 0.04
- chronotype measurement · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q2QD12-F1 | alphafold | PREDICTED | 96.49 | — |
Amino-acid sequence (228 residues)
MASGCKIGPS ILNSDLANLG AKCLQMLDSG ADYLHLDVMD GHFVPNITFG HPVVESLRKQ LGQDPFFDMH MMVSKPEQWV KPMAVAEANQ YTFHLEATEN PGTLIKDIRE NGMKVGLAIK PGTSVEYLAP WANQIDMALV MTVEPGFGEQ KFMEDMMPKV HWLRTQFPSL DIEGDGGVGS DTVHKCAEAG ANMTVSGSAI MRSEDPRSVI NLLRNICSEA AQKRSLDR
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