About Zinc finger protein ZXDC
Zinc finger protein ZXDC (ZXDC) is a protein
from Homo sapiens identified by UniProt accession
Q2QGD7, 858 residues long.
MolForge cross-references it against 0 known binders and
12 disease associations.
Target properties
| Protein name | Zinc finger protein ZXDC |
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| UniProt accession | Q2QGD7 |
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| Gene | ZXDC |
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| Organism | Homo sapiens |
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| Length | 858 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (12)
Diseases linked to this target (Open Targets).
- heel bone mineral density · score 0.30
- lymphocyte count · score 0.26
- age at menopause · score 0.23
- mean platelet volume · score 0.04
- platelet count · score 0.04
- hemoglobin measurement · score 0.03
- hematocrit · score 0.03
- hair shape measurement · score 0.02
- cancer · score 0.01
- lymph node metastatic carcinoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q2QGD7-F1 | alphafold | PREDICTED | 51.37 | — |
Amino-acid sequence (858 residues)
MDLPALLPAP TARGGQHGGG PGPLRRAPAP LGASPARRRL LLVRGPEDGG PGARPGEASG PSPPPAEDDS DGDSFLVLLE VPHGGAAAEA AGSQEAEPGS RVNLASRPEQ GPSGPAAPPG PGVAPAGAVT ISSQDLLVRL DRGVLALSAP PGPATAGAAA PRRAPQASGP STPGYRCPEP QCALAFAKKH QLKVHLLTHG GGQGRRPFKC PLEGCGWAFT TSYKLKRHLQ SHDKLRPFGC PVGGCGKKFT TVYNLKAHMK GHEQESLFKC EVCAERFPTH AKLSSHQRSH FEPERPYKCD FPGCEKTFIT VSALFSHNRA HFREQELFSC SFPGCSKQYD KACRLKIHLR SHTGERPFIC DSDSCGWTFT SMSKLLRHRR KHDDDRRFTC PVEGCGKSFT RAEHLKGHSI THLGTKPFEC PVEGCCARFS ARSSLYIHSK KHVQDVGAPK SRCPVSTCNR LFTSKHSMKA HMVRQHSRRQ DLLPQLEAPS SLTPSSELSS PGQSELTNMD LAALFSDTPA NASGSAGGSD EALNSGILTI DVTSVSSSLG GNLPANNSSL GPMEPLVLVA HSDIPPSLDS PLVLGTAATV LQQGSFSVDD VQTVSAGALG CLVALPMKNL SDDPLALTSN SNLAAHITTP TSSSTPRENA SVPELLAPIK VEPDSPSRPG AVGQQEGSHG LPQSTLPSPA EQHGAQDTEL SAGTGNFYLE SGGSARTDYR AIQLAKEKKQ RGAGSNAGAS QSTQRKIKEG KMSPPHFHAS QNSWLCGSLV VPSGGRPGPA PAAGVQCGAQ GVQVQLVQDD PSGEGVLPSA RGPATFLPFL TVDLPVYVLQ EVLPSSGGPA GPEATQFPGS TINLQDLQ
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