About Mpv17-like protein
Mpv17-like protein (MPV17L) is a protein
from Homo sapiens identified by UniProt accession
Q2QL34, 196 residues long.
MolForge cross-references it against 0 known binders and
31 disease associations.
Target properties
| Protein name | Mpv17-like protein |
|---|
| UniProt accession | Q2QL34 |
|---|
| Gene | MPV17L |
|---|
| Organism | Homo sapiens |
|---|
| Length | 196 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (31)
Diseases linked to this target (Open Targets).
- triglyceride measurement · score 0.31
- sleep duration · score 0.30
- Testicular Germ Cell Tumor · score 0.10
- MODY · score 0.08
- glycerophospholipid measurement · score 0.06
- blood metabolite measurement · score 0.06
- chronic pancreatitis · score 0.05
- diabetes mellitus, transient neonatal, 2 · score 0.05
- reticulocyte count · score 0.04
- hyperinsulinemic hypoglycemia, familial, 2 · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q2QL34-F1 | alphafold | PREDICTED | 85.67 | — |
Amino-acid sequence (196 residues)
MAGWWPALSR AARRHPWPTN VLLYGSLVSA GDALQQRLQG REANWRQTRR VATLVVTFHA NFNYVWLRLL ERALPGRAPH ALLAKLLCDQ VVGAPIAVSA FYVGMSILQG KDDIFLDLKQ KFWNTYLSGL MYWPFVQLTN FSLVPVQWRT AYAGVCGFLW ATFICFSQQS GDGTFKSAFT ILYTKGTSAT EGYPKK
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