About Brorin
Brorin (VWC2) is a protein
from Homo sapiens identified by UniProt accession
Q2TAL6, 325 residues long.
MolForge cross-references it against 0 known binders and
26 disease associations.
Target properties
| Protein name | Brorin |
|---|
| UniProt accession | Q2TAL6 |
|---|
| Gene | VWC2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 325 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (26)
Diseases linked to this target (Open Targets).
- self reported educational attainment · score 0.43
- blood protein measurement · score 0.43
- body mass index · score 0.35
- C-reactive protein measurement · score 0.32
- neurodegenerative disease · score 0.27
- age at first birth measurement · score 0.22
- sitting height measurement · score 0.21
- body height · score 0.21
- insomnia measurement · score 0.15
- tuberculosis · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q2TAL6-F1 | alphafold | PREDICTED | 68.41 | — |
Amino-acid sequence (325 residues)
MPSSTAMAVG ALSSSLLVTC CLMVALCSPS IPLEKLAQAP EQPGQEKREH ASRDGPGRVN ELGRPARDEG GSGRDWKSKS GRGLAGREPW SKLKQAWVSQ GGGAKAGDLQ VRPRGDTPQA EALAAAAQDA IGPELAPTPE PPEEYVYPDY RGKGCVDESG FVYAIGEKFA PGPSACPCLC TEEGPLCAQP ECPRLHPRCI HVDTSQCCPQ CKERKNYCEF RGKTYQTLEE FVVSPCERCR CEANGEVLCT VSACPQTECV DPVYEPDQCC PICKNGPNCF AETAVIPAGR EVKTDECTIC HCTYEEGTWR IERQAMCTRH ECRQM
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