About Zinc finger protein 800
Zinc finger protein 800 (ZNF800) is a protein
from Homo sapiens identified by UniProt accession
Q2TB10, 664 residues long.
MolForge cross-references it against 0 known binders and
62 disease associations.
Target properties
| Protein name | Zinc finger protein 800 |
|---|
| UniProt accession | Q2TB10 |
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| Gene | ZNF800 |
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| Organism | Homo sapiens |
|---|
| Length | 664 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (62)
Diseases linked to this target (Open Targets).
- alkaline phosphatase measurement · score 0.57
- lean body mass · score 0.47
- heel bone mineral density · score 0.47
- Red cell distribution width · score 0.46
- lymphocyte percentage of leukocytes · score 0.44
- neutrophil percentage of leukocytes · score 0.44
- lymphocyte count · score 0.43
- appendicular lean mass · score 0.42
- body weight · score 0.42
- reticulocyte count · score 0.41
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q2TB10-F1 | alphafold | PREDICTED | 61.68 | — |
Amino-acid sequence (664 residues)
MPLRDKYCQT DHHHHGCCEP VYILEPGDPP LLQQPLQTSK SGIQQIIECF RSGTKQLKHI LLKDVDTIFE CKLCRSLFRG LPNLITHKKF YCPPSLQMDD NLPDVNDKQS QAINDLLEAI YPSVDKREYI IKLEPIETNQ NAVFQYISRT DNPIEVTESS STPEQTEVQI QETSTEQSKT VPVTDTEVET VEPPPVEIVT DEVAPTSDEQ PQESQADLET SDNSDFGHQL ICCLCRKEFN SRRGVRRHIR KVHKKKMEEL KKYIETRKNP NQSSKGRSKN VLVPLSRSCP VCCKSFATKA NVRRHFDEVH RGLRRDSITP DIATKPGQPL FLDSISPKKS FKTRKQKSSS KAEYNLTACK CLLCKRKYSS QIMLKRHMQI VHKITLSGTN SKREKGPNNT ANSSEIKVKV EPADSVESSP PSITHSPQNE LKGTNHSNEK KNTPAAQKNK VKQDSESPKS TSPSAAGGQQ KTRKPKLSAG FDFKQLYCKL CKRQFTSKQN LTKHIELHTD GNNIYVKFYK CPLCTYETRR KRDVIRHITV VHKKSSRYLG KITASLEIRA IKKPIDFVLN KVAKRGPSRD EAKHSDSKHD GTSNSPSKKY EVADVGIEVK VTKNFSLHRC NKCGKAFAKK TYLEHHKKTH KANASNSPEG NKTKGRSTRS KALV
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