Cell adhesion molecule CEACAM16 (CEACAM16)

About Cell adhesion molecule CEACAM16

Cell adhesion molecule CEACAM16 (CEACAM16) is a protein from Homo sapiens identified by UniProt accession Q2WEN9, 425 residues long. MolForge cross-references it against 0 known binders and 62 disease associations.

Target properties

Protein name	Cell adhesion molecule CEACAM16
UniProt accession	Q2WEN9
Gene	CEACAM16
Organism	Homo sapiens
Length	425 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (62)

Diseases linked to this target (Open Targets).

autosomal dominant nonsyndromic hearing loss · score 0.62
hearing loss, autosomal recessive · score 0.57
nonsyndromic genetic hearing loss · score 0.52
ear malformation · score 0.27
Rare genetic deafness · score 0.27
Abnormality of the ear · score 0.27
apolipoprotein B measurement · score 0.20
genetic disorder · score 0.19
Hearing impairment · score 0.16
deafness · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q2WEN9-F1	alphafold	PREDICTED	90.24	—

Amino-acid sequence (425 residues)

MALTGYSWLL LSATFLNVGA EISITLEPAQ PSEGDNVTLV VHGLSGELLA YSWYAGPTLS VSYLVASYIV STGDETPGPA HTGREAVRPD GSLDIQGILP RHSGTYILQT FNRQLQTEVG YGHVQVHEIL AQPTVLANST ALVERRDTLR LMCSSPSPTA EVRWFFNGGA LPVALRLGLS PDGRVLARHG IRREEAGAYQ CEVWNPVSVS RSEPINLTVY FGPERVAILQ DSTTRTGCTI KVDFNTSLTL WCVSRSCPEP EYVWTFNGQA LKNGQDHLNI SSMTAAQEGT YTCIAKNTKT LLSGSASVVV KLSAAAVATM IVPVPTKPTE GQDVTLTVQG YPKDLLVYAW YRGPASEPNR LLSQLPSGTW IAGPAHTGRE VGFPNCSLLV QKLNLTDTGR YTLKTVTVQG KTETLEVELQ VAPLG

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards