About Zinc finger protein 699
Zinc finger protein 699 (ZNF699) is a protein
from Homo sapiens identified by UniProt accession
Q32M78, 642 residues long.
MolForge cross-references it against 0 known binders and
28 disease associations.
Target properties
| Protein name | Zinc finger protein 699 |
|---|
| UniProt accession | Q32M78 |
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| Gene | ZNF699 |
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| Organism | Homo sapiens |
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| Length | 642 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (28)
Diseases linked to this target (Open Targets).
- DEGCAGS syndrome · score 0.64
- complex neurodevelopmental disorder · score 0.37
- genetic disorder · score 0.19
- Blackfan-Diamond anemia · score 0.12
- Diamond-Blackfan anemia · score 0.12
- appendicular lean mass · score 0.06
- neutrophil count · score 0.04
- serum gamma-glutamyl transferase measurement · score 0.04
- alcohol dependence · score 0.02
- axial length measurement · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q32M78-F1 | alphafold | PREDICTED | 70.54 | — |
Amino-acid sequence (642 residues)
MEEERKTAEL QKNRIQDSVV FEDVAVDFTQ EEWALLDLAQ RNLYRDVMLE NFQNLASLGY PLHTPHLISQ WEQEEDLQTV KRELIQGIFM GEHREGFETQ LKTNESVASQ DICGEKISNE QKIVRFKRND SWFSSLHENQ ESCGIDYQNK SHERHLRNHM VENIYECYEE NQDGQTFSQV PNLDSLKRNT EVKSCECHEC GKAFVDHSSL KSHIRSHTGS KPYQCKECGK AFHFLACFKK HMKTPTEEKP YECKECTKAF SCSSFFRAHM KIHIGKTNYE CKECGKGFSC SSSLTEHKRI HSGDKPYECK ECGKAFSCSS SLSKHKRIHS GDKPYECKEC GKAFSSSSHL IIHIRIHTGE KPYECKECGK AFSESSKLTV HGRTHTGEKP YKCKECGKAY NCPSSLSIHM RKHTGEKPYE CLECGKAFYL PTSLNTHVKN QSREKPYECK ECGKAFSCPS SFRAHVRDHT GKIQYECKEC GKTFSRSSSL TEHLRTHSGE KPYECKECGK AFISSSHLTV HIRTHTGEKP YECKKCGKAF IYPSALRIHM RTHTGEKPYE CKECGKAFRH SSYLTVHARM HTGEKPFECL ECGKAFSCPS SFRRHVRSHT GEKPYECKEC GKAFVCPAYF RRHVKTHTRE NI
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