BTB/POZ domain-containing protein 16 (BTBD16)

About BTB/POZ domain-containing protein 16

BTB/POZ domain-containing protein 16 (BTBD16) is a protein from Homo sapiens identified by UniProt accession Q32M84, 506 residues long. MolForge cross-references it against 0 known binders and 60 disease associations.

Target properties

Protein name	BTB/POZ domain-containing protein 16
UniProt accession	Q32M84
Gene	BTBD16
Organism	Homo sapiens
Length	506 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (60)

Diseases linked to this target (Open Targets).

heel bone mineral density · score 0.34
bone density · score 0.30
alcohol consumption measurement · score 0.27
pulse pressure measurement · score 0.27
progression free survival · score 0.16
chronic lymphocytic leukemia · score 0.16
attention deficit hyperactivity disorder · score 0.15
antisocial behaviour measurement · score 0.15
substance abuse · score 0.15
cortical thickness · score 0.13

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q32M84-F1	alphafold	PREDICTED	78.78	—

Amino-acid sequence (506 residues)

MIMSNTHKAR LERRVTGSTN RWRLPKQPFS GDLLSLSQMC KALSIDFEEA LRNPDRLCIS QIQKFFFENF KNKDIQSGEA DVILECLGFK WELHQPQLFQ SETLAKLYLK ALAQGTTHPL RELEELLRAQ SPKKTKEKSP AKRIIISLKI NDPLVTKVAF ATALKNLYMS EVEINLEDLL GVLASAHILQ FSGLFQRCVD VMIARLKPST IKKFYEAGCK YKEEQLTTGC EKWLEMNLVP LGGTQIHLHK IPQDLLHKVL KSPRLFTFSE FHLLKTMLLW VFLQLNYKIQ AIPTYETVMT FFKSFPENCC FLDRDIGRSL RPLFLCLRLH GITKGKDLEV LRHLNFFPES WLDQVTVNHY HALENGGDMV HLKDLNTQAV RFGLLFNQEN TTYSKTIALY GFFFKIKGLK HDTTSYSFYM QRIKHTDLES PSAVYEHNHV SLRAARLVKY EIRAEALVDG KWQEFRTNQI KQKFGLTTSS CKSHTLKIQT VGIPIYVSFA FIFPAS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards