Atos homolog protein A (ATOSA)

About Atos homolog protein A

Atos homolog protein A (ATOSA) is a protein from Homo sapiens identified by UniProt accession Q32MH5, 1076 residues long. MolForge cross-references it against 0 known binders and 26 disease associations.

Target properties

Protein name	Atos homolog protein A
UniProt accession	Q32MH5
Gene	ATOSA
Organism	Homo sapiens
Length	1076 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (26)

Diseases linked to this target (Open Targets).

sex hormone-binding globulin measurement · score 0.36
PHF-tau measurement · score 0.34
high density lipoprotein cholesterol measurement · score 0.32
serum alanine aminotransferase measurement · score 0.32
testosterone measurement · score 0.27
drug use measurement · score 0.14
body mass index · score 0.13
body height · score 0.07
waist-hip ratio · score 0.07
protein measurement · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q32MH5-F1	alphafold	PREDICTED	54.92	—

Amino-acid sequence (1076 residues)

MKPDRDTLDE YFEYDAEEFL VSLALLITEG RTPECSVKGR TESFHCPPAQ SCYPVTTKHE CSDKLAQCRQ ARRTRSEVTL LWKNNLPIMV EMMLLPDCCY SDDGPTTEGI DLNDPAIKQD ALLLERWILE PVPRQNGDRF IEEKTLLLAV RSFVFFSQLS AWLSVSHGAI PRNILYRISA ADVDLQWNFS QTPIEHVFPV PNVSHNVALK VSVQSLPRQS NYPVLTCSIH TNIGLYEKRI QQHKLKTHQH HNPNEAEQCG TNSSQRLCSK QTWTMAPESV LHAKSGPSPE YTAAVKNIKL YPGTGSKSDH GTSQANILGF SGIGDIKSQE TSVRTLKSFS MVDSSISNRQ SFWQSAGETN PLIGSLIQER QEIIARIAQH LIHCDPSTSH VSGRPFNTQE SSSLHSKLFR VSQENENVGK GKEAFSMTFG SPEFSSPEDT NEGKIRLKPE TPRSETCISN DFYSHMPVGE TNPLIGSLLQ ERQDVIARIA QHLEHIDPTA SHIPRQSFNM HDSSSVASKV FRSSYEDKNL LKKNKDESSV SISHTKCSLL GDISDGKNLV PNKCFTSFKN NSKEKCSLKH QTRNQCQNNP SEIIQSTYQE TQNKSSSLST SSILSQHKEN NLDLTSRFKE QEMSNGIDKQ YSNCTTIDKQ ICTNKYKEKI INENYNPKFF GNLQSDDSKK NDSKIKVTVL EMSEYLNKYE SMSSNKDSKR PKTCEQNTQL NSIENYLNKD NEGFKCKKSD QLKNEQDKQE DPTNEKSQNY SQRRSIKDCL STCEQPKNTE VLRTTLKHSN VWRKHNFHSL DGTSTRAFHP QTGLPLLSSP VPQRKTQSGC FDLDSSLLHL KSFSSRSPRP CLNIEDDPDI HEKPFLSSSA PPITSLSLLG NFEESVLNYR FDPLGIVDGF TAEVGASGAF CPTHLTLPVE VSFYSVSDDN APSPYMGVIT LESLGKRGYR VPPSGTIQVT LFNPNKTVVK MFVVIYDLRD MPANHQTFLR QRTFSVPVKQ EVKRSVNKEN IRHTEERLLR YLIHLRFQSS KSGKIYLHRD VRLLFSRKSM EVDSGAAYEL KSYTESPTNP QFSPRC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards